A Doctor’s Guide to the 6 FDA‑Approved Neurotoxins: Botox Dysport Xeomin Jeaveau Letybo and Daxxify: A Definitive Comparison
What is the Core Mechanism of Action for All FDA-Approved Neurotoxins?
All six FDA-approved neurotoxins, whether Botox, Dysport, Xeomin, Jeuveau, Letybo, or Daxxify, share the same active molecular weapon: botulinum toxin type A. This article is A Doctor’s Guide to the 6 FDA-Approved Neurotoxins: Botox Dysport Xeomin Jeaveau Letybo y Daxxify.
When injected into targeted muscles, the toxin blocks the release of a key neurotransmitter (acetylcholine) at the nerve‑muscle junction, effectively “turning off” the signal telling that muscle to contract. As a result, dynamic wrinkles, those created by repeated expresiones faciales, relax and gradually soften as the underlying muscle becomes temporarily inactive.
This core mechanism is what makes them “wrinkle relaxers,” “neuromodulators,” or “neurotoxins.” Whether treating forehead lines, frown (glabellar) lines, patas de gallo, or even medically‑indicated conditions like migraines or neck bands, the principle remains the same: muscle activity reduction leads to smoother overlying skin.
Índice
1. Why Are All 6 Neurotoxins Considered Equivalents, Even Though Their Formulations Differ?
2. What Is the Onset and Duration for Each Neurotoxin, Onset Speed vs. Longevity?
3. How Do Formulation Differences (Proteins, Peptides, Purity) Affect Results and Immunogenicity?
4. Is There a Standard Unit Conversion Ratio Between Brands Like Dysport, Botox, and Daxxify?
5. In Which Areas or Muscle Groups Does Wider Spread (Diffusion) Offer a Distinct Advantage?
6. What Makes Some Neurotoxins Better for Precision Work, Small Areas vs. Large Areas?
7. How Does Each Neurotoxin Compare for Common Cosmetic Goals (Forehead, Frown Lines, Crow’s Feet, Lower Face)?
8. Which Neurotoxin Is Best for Therapeutic Use, e.g., Migraines, Hyperhidrosis, Neck Bands, Jaw / Masseter?
9. What Are the Risks and Side Effects, including Swelling, Spread, Resistance, and Other Rare Events?
10. How do Cost, Per Unit, Per Session, and Annually Compare Across Brands?
11. What Should a Doctor Consider When Choosing the Best Neurotoxin for a First-Time Patient?
12. When and Why Might a Patient Switch Neurotoxins, Waning Effects, Resistance, or Personal Preference?
13. Are the Newest Neurotoxins (Letybo and Daxxify) Worth the Hype Over the Classics?
14. How to Optimize Injection Strategy and Aftercare, Injection Site Mapping, Dosage, Timing, and Maintenance Schedule?
15. Preguntas más frecuentes (FAQ)
16. Conclusión
17. Referencias
1. Why Are All 6 Neurotoxins Considered Equivalents, Even Though Their Formulations Differ?
Although these six injections share the same active botulinum toxin type A, their differences lie in the formulation: stabilizing proteins or peptides, purification processes, and excipients.
Formulation differences affect how the toxin behaves: how much it spreads, how quickly it works, how long its effects last, and how likely the body is to develop resistance over time. For instance, some products include accessory proteins (which help stabilize the toxin), while others strip them out, using only the “pure neurotoxin” molecule, which can matter for long‑term use.
That’s why, even though they all technically do the same thing, licensed medical providers consider them distinct tools in a toolkit and choose the one that best matches the patient’s goals, anatomy, lifestyle, and history. The term “FDA-approved neurotoxin comparison” becomes especially useful in making that decision.
2. What Is the Onset and Duration for Each Neurotoxin, Onset Speed vs. Longevity?
One key difference among the six is how quickly they begin to work (onset) and how long the results typically last (duration).
- Dysport and sometimes Jeuveau show effects more quickly, often within 2–5 days.
- Botox and Xeomin usually begin to take effect a little slower, roughly 3–7 days.
- Daxxify stands out: in many patients, the onset can be as fast as 1–2 days.
In terms of duration:
- Botox, Dysport, Xeomin, Jeuveau, and Letybo generally last about 3–4 months.
- Daxxify, thanks to its novel peptide stabilization, tends to last much longer, often up to 6 months, and some patients even report 8–9 months before needing touch‑ups.
For patients hoping to minimize maintenance visits, Daxxify has rapidly gained attention as the longest-lasting wrinkle relaxer.
3. How Do Formulation Differences (Proteins, Peptides, Purity) Affect Results and Immunogenicity?
A major differentiating factor between brands is whether they include stabilizing proteins (accessory proteins), or use a purified “naked” toxin, or a peptide-based stabilizer.
- For example, Xeomin is considered the “pure neurotoxin” option because it removes complexing proteins entirely, leaving just the core active molecule.
- Daxxify takes a different approach: it uses a proprietary peptide (rather than human serum albumin or animal proteins) to stabilize the toxin. That peptide helps the toxin bind firmly to nerve receptors, which may contribute to longer duration and potentially lower risk of immune reactions.
- Traditional brands like Botox, Dysport, and Jeuveau include accessory proteins and albumin to stabilize the toxin, which helps with shelf‑life and storage, but, in rare cases, may increase immunogenicity (the risk that the body develops antibodies that reduce efficacy over time).
Because of that, for patients worried about “botulinum toxin resistance risk,” or who’ve had many treatments over a long period, Xeomin or Daxxify may be recommended.
4. Is There a Standard Unit Conversion Ratio Between Brands Like Dysport, Botox, and Daxxify?
It’s important to understand that “units” are not interchangeable across brands; one unit of Botox does not equal one unit of Dysport, Xeomin, or Daxxify.
For example, Dysport typically requires roughly 2.5 to 3 times as many units as Botox to achieve a similar wrinkle‑relaxing effect.
Daxxify may use about 2 times as many “units” of Botox in a given area, but because of its peptide-based stabilization, those units don’t translate directly on a 1:1 potency basis.
For these reasons, when switching between brands (e.g., “Dysport vs Botox unit conversion”), it’s not enough to count units; an experienced injector will tailor dosage based on anatomical area, muscle strength, and prior response.
5. In Which Areas or Muscle Groups Does Wider Spread (Diffusion) Offer a Distinct Advantage?
One of the key considerations when choosing a neurotoxin brand is how much the product diffuses or “spreads” after injection. This can be an advantage or a drawback depending on the treatment area.
For larger, broader muscles, such as the forehead (frontalis) or the neck (platysma), a toxin that diffuses more readily can smooth a large area efficiently. That’s why Dysport, with its tendency to spread, is often preferred for forehead lines, neck bands, and even “masseter Botox contouring” and trapezius/shoulder injections for slimming or muscle relaxation.
On the other hand, for small, precise zones, like the corners of the mouth (DAO), around the eyes (crow’s feet), or for a subtle brow lift, minimal spread is desirable to avoid affecting adjacent muscles. In those cases, classic Botox or a “tight” formulation (such as Xeomin or Daxxify) may be better suited.
Thus, the diffusion characteristic affects the injection strategy: “spread vs precision.” An innovative provider tailors the choice to the patient’s anatomy and aesthetic objetivos.
6. What Makes Some Neurotoxins Better for Precision Work, Small Areas vs. Large Areas?
Precision matters when tiny muscle groups control delicate expressions. For small zones where you want predictable results, such as fine lip lines, corners of the mouth (for a “mouth corner lift”), or around the eyes, a neurotoxin that stays localized is key.
In this regard, Botox is long regarded as “the gold standard.” Its protective protein coat (albumin-based) helps stabilize and localize the molecule, reducing the risk of “drift.”
That’s why many doctors choose Botox for tasks such as gummy smile correction, DAO (mouth corner) lifts, or subtle lip enhancements.
Likewise, highly purified formulas such as Xeomin (a pure neurotoxin) or Daxxify (peptide-stabilized) offer tight, controlled diffusion, appealing to first-time patients or those seeking very natural, precise results.
In short, for large muscle areas and broad smoothing, diffusion helps; for fine-tuned, anatomically complex zones, precision prevails.
7. How Does Each Neurotoxin Compare for Common Cosmetic Goals (Forehead, Frown Lines, Crow’s Feet, Lower Face)?
Let’s break down which neurotoxin tends to perform best depending on the treatment goal:
- Forehead Lines & Broad Horizontal Wrinkles: Because of its diffusion and smoothing effect, Dysport is often the preferred neurotoxin for forehead work. Its ability to spread across the wide frontalis muscle means fewer puntos de inyección and a softer, more “airbrushed” result.
- Glabellar (Frown) Lines, the “11s” between the brows: Several options perform well here. Many providers use Botox or Jeuveau. Jeuveau was developed exclusively for aesthetic use and may offer a competitive cost-benefit ratio for younger patients or for preventive treatments.
- Crow’s Feet (around the eyes) and Fine Lines: For subtle, delicate treatment, especially near thin skin or muscles controlling subtle expressions, Botox or a “pure / peptide” neurotoxin (Xeomin, Daxxify) often offers the most controlled, natural-looking outcome.
- Lower Face, Jawline, Masseter, Neck Bands, Platysma: For larger muscle groups or contouring (e.g., slimming the jaw, neck rejuvenation), Dysport’s diffusion can be beneficial. Some injectors may also choose Dysport or Letybo for platysma or neck‑band work.
- Preventative / “Prejuvenation” for Younger Patients: For patients new to neuromodulators, less diffusion, controlled onset, and a gentle learning curve make Botox, Xeomin, or Jeuveau good first picks. They offer reliable effects without excessive “toxicity,” and allow gradual adaptation.
8. Which Neurotoxin Is Best for Therapeutic Use, e.g., Migraines, Hyperhidrosis, Neck Bands, Jaw / Masseter?
It’s important to remember that these injectables are not only cosmetic; many are also FDA‑approved for medical conditions or used off‑label for therapeutic benefit.
- For chronic migraines, the long‑proven track record of Botox makes it the go‑to choice, since it is FDA‑approved for migraine prevention and has extensive clinical experience.
- For hyperhidrosis (sudoración excesiva), neck bands (platysma), jaw tension/masseter hypertrophy, or muscle spasm, classic formulations like Botox, or sometimes Dysport, remain commonly used due to familiarity, dosing flexibility, and broad U.S. clinical usage.
- For patients with a history of immunogenicity or resistance, “clean” toxins such as Xeomin (a pure neurotoxin) may be particularly valuable.
Thus, therapeutic versus aesthetic use may influence toxin choice just as much as wrinkle‑relaxing goals.
9. What Are the Risks and Side Effects, Including Swelling, Spread, Resistance, and Other Rare Events?
When administered by experienced, licensed providers, all six FDA-approved neurotoxins are considered safe.
Common side effects tend to be mild: localized injection‑site swelling, redness, bruising, or temporary tenderness are among the most reported.
In rare cases, more significant issues can occur, such as a droopy eyelid (ptosis), unintended diffusion leading to weakness in adjacent muscles, or systemic effects if the toxin spreads.
Another concern over long-term repeated use is immunogenicity: the development of antibodies against the toxin’s accessory proteins, reducing treatment effectiveness (resistance). Formulations that minimize or avoid the use of additional proteins (such as Xeomin or Daxxify) may lower this risk.
10. How Does Cost, Per Unit, Per Session, and Annually, Compare Across Brands?
Cost varies widely depending on the provider, geographic region, and number of units used. For example, the typical per‑unit coste del Botox ranges from about $10 to $25, depending on the locale.
Because units are not interchangeable, a Dysport session may require more units, thereby increasing the total cost even though individual units are cheaper.
With longer-lasting neurotoxins like Daxxify, a longer interval between treatments (6–9 months) may lead to lower annual costs, fewer visits, and fewer redoses, which, for many patients, offsets the higher per-session cost.
11. What Should a Doctor Consider When Choosing the Best Neurotoxin for a First-Time Patient?
When working with a first-time user, a doctor must weigh multiple factors: the patient’s aesthetic goals, their muscle strength and anatomy, how “natural” they want the result to look, their tolerance for frequent visits, and risk factors such as potential immunogenicity or sensitivity.
For someone seeking subtle, controlled, and reversible results, especially in delicate or small areas, a product with minimal diffusion or a “clean” formulation (like Xeomin or Daxxify) may be ideal. For patients wanting broader smoothing with fewer injection points, something like Dysport might be more efficient.
Also consider maintenance: if the patient prefers fewer touch‑ups, a longer‑lasting neurotoxin (like Daxxify) may be a better option. If they prefer trial-and-error, more flexibility, or are cautious about long-term effects, starting with a classic like Botox might be safer.
Ultimately, the “best” neurotoxin for a new patient isn’t a one-size-fits-all; it’s the one that fits their goals, anatomy, lifestyle, and comfort level.
12. When and Why Might a Patient Switch Neurotoxins, Waning Effects, Resistance, or Personal Preference?
There are several scenarios where switching between neurotoxins makes sense.
If a patient notices that their usual toxin isn’t working as well (waning effect), or they’ve developed antibody resistance to a formulation containing accessory proteins, switching to a purified toxin like Xeomin or peptide-based like Daxxify may restore effectiveness.
Alternatively, if a patient wants to shorten or lengthen maintenance intervals, perhaps fewer visits with longer-lasting results, they might switch to a long-lasting option such as Daxxify. If they want more control, subtlety, or a less “frozen” look, they might switch to a more precise neurotoxin or adjust dosage.
Some patients may also switch simply because their aesthetic goals change over time: more smoothing in one area, more muscle relaxation elsewhere, or moving from cosmetic use (wrinkles) to therapeutic uses (e.g., neck bands, masseter, hyperhidrosis).
13. Are the Newest Neurotoxins (Letybo and Daxxify) Worth the Hype Over the Classics?
The arrival of newer FDA‑approved injectables like Letybo and Daxxify reflects a trend toward innovation in neuromodulators, and for good reason.
- Daxxify, with its peptide stabilization, delivers noticeable advantages: faster onset (often 1–2 days), much more extended duration (6–9 months in many), and no human/animal proteins, which may lower resistance risk. For patients who metabolize toxins quickly (so-called “burn through” Botox), Daxxify can be a game-changer.
- Letybo, recently FDA‑approved in 2024 in the U.S., brings another choice for injectors and patients, especially those familiar with global aesthetic trends (it has been popular in South Korea). Its safety record abroad, plus its diffusion and effect profile, make it a serious contender.
That said, classics like Botox, Dysport, and Xeomin remain indispensable for their long-term data, versatility (cosmetic and therapeutic uses), and familiarity among providers. The “newbies” aren’t necessarily “better” across the board, but they’re valuable tools in estética moderna práctica.
14. How to Optimize Injection Strategy and Aftercare, Injection Site Mapping, Dosage, Timing, and Maintenance Schedule?
A savvy injector will first assess the patient’s facial anatomy, muscle strength, and aesthetic goals and then choose the neurotoxin brand, dilution, injection site mapping, and dose accordingly. For example:
- For forehead lines, fewer injection points may be used if a diffusing toxin (like Dysport) is selected.
- For delicate areas like the eyes or mouth, small, precise doses of a “tight” toxin (Botox, Xeomin, Daxxify) may minimize the risk of spread.
- For lower‑face contouring (masseter, platysma), dosage and spread must be carefully managed to avoid functional weakness (chewing, swallowing).
Aftercare is also key: patients should avoid strenuous exercise, excessive facial movement, or lying flat for several hours after injection. Maintenance visits should be scheduled based on how long the toxin lasts; for many, that means every 3–4 months; for Daxxify, maybe twice a year.
Finally, for long-term use, rotating between neurotoxins or using lower-protein/peptide formulations may help reduce immunogenicity and prolong efficacy.
15. Frequently Asked Questions (FAQs) about A Doctor’s Guide to the 6 FDA-Approved Neurotoxins: Botox Dysport Xeomin Jeaveau Letybo y Daxxify
Q1. Is Letybo better than Xeomin?
Respuesta concisa: Not necessarily, they excel in different ways depending on your goals.
Respuesta detallada: Letybo and Xeomin both use botulinum toxin A but differ in formulation and historical use. Xeomin is a “naked” neurotoxin (no accessory proteins), which may lower the chance of resistance and can be ideal for long‑term maintenance.
Letybo is newer, with promising clinical data and a global history, and may offer efficacy similar to that of classic toxins. Still, because it’s newer in the U.S., less long-term data is available.
For some patients, Xeomin’s purity may be advantageous; for others seeking a newer product, perhaps influenced by global aesthetic trends, Letybo may be preferred.
Q2. What is better, Botox, Dysport, or Jeuveau?
Respuesta concisa: It depends on your treatment area, how quickly you want results, and how natural you want the outcome to be.
Respuesta detallada: Botox is the time‑tested “gold standard,” excellent for precision work and for therapeutic uses (like migraines or neck bands). Dysport tends to diffuse more widely, making it a good choice for larger areas like the forehead or neck where a smooth, broad effect is needed.
Jeuveau, explicitly developed for cosmetic use, can be a cost‑effective entry point, especially for younger patients or first-time users. Ultimately, “better” is personal: a skilled doctor chooses the toxin that matches your anatomy and goals.
Q3. What is the difference between Daxxify and Xeomin?
Respuesta concisa: The main differences are formulation, onset, and duration.
Respuesta detallada: Both are botulinum toxin A products, but Xeomin is a purified “naked” toxin without accessory proteins. At the same time, Daxxify uses a unique peptide-based stabilizer that enhances binding and prolongs the effect.
Xeomin tends to have a standard onset and duration (similar to Botox). At the same time, Daxxify often works faster (1–2 days) and lasts much longer (6–9 months), making it attractive for those wanting fewer treatments.
Q4. Is Jeuveau the same as Letybo?
Respuesta concisa: No. They are different neurotoxin brands with different formulations and approval histories.
Respuesta detallada: Jeuveau (prabotulinumtoxinA) and Letybo (letibotulinumtoxinA) are distinct products. Jeuveau has been on the U.S. market longer and is positioned as a cosmetic-only injectable.
Letybo is newer and may offer different spread or diffusion characteristics. Their molecular formulations, stabilizers, and global usage backgrounds differ, so they are not interchangeable.
Q5. Which neurotoxin brand has the softest, most natural-looking results?
Respuesta concisa: Often Xeomin or Daxxify, but a skilled injector using Botox can also achieve natural-looking results.
Respuesta detallada: Because Xeomin is a pure neurotoxin and Daxxify uses a peptide stabilizer, both can be dosed in a way that yields subtle, soft, natural-looking relaxation rather than a “frozen” look. Their controlled diffusion helps maintain natural movement.
However, with the proper technique and conservative dosing, Botox remains a top choice for natural-looking results, too.
Q6. Why is my Botox not lasting as long as it used to? Am I becoming resistant?
Respuesta concisa: Possibly. Repeated use can lead to antibody development, reducing effectiveness.
Respuesta detallada: Over time, especially with repeated injections of toxins containing accessory proteins, the body may form antibodies that neutralize the toxin, leading to reduced duration or efficacy (resistance). Using a pure toxin (e.g., Xeomin) or a peptide-based formulation (e.g., Daxxify) might reduce this risk.
Other factors, such as metabolism, dilution, técnica de inyección, and muscle strength, can also influence how long results last.
Q7. Which neurotoxin is the best choice for tratamiento de la sudoración excesiva (hyperhidrosis)?
Respuesta concisa: Classic, well‑studied toxins like Botox are often preferred for the treatment of hyperhidrosis.
Respuesta detallada: Because hyperhidrosis treatment requires precise dosing over relatively large surface areas (e.g., armpits, palms), experienced providers often use trusted neurotoxins with proven safety data, such as Botox or Dysport.
These choices reflect long-term clinical experience and versatility beyond purely cosmetic uses.
Q8. Does Xeomin truly have fewer risks of causing a droopy eyelid compared to Botox?
Respuesta concisa: Potentially. Because Xeomin is a pure neurotoxin with minimal diffusion, the risk may be lower if injected carefully.
Respuesta detallada: Droopy eyelid (ptosis) often results from unintended spread affecting nearby muscles. Xeomin’s purified, “tight” formulation may reduce diffusion compared to toxins with accessory proteins, thereby lowering this risk, especially when administered by a skilled injector.
Nonetheless, technique and anatomy remain critical factors.
Q9. I’m a first-time user; should I start with Botox or a newer brand like Jeuveau?
Respuesta concisa: Both are reasonable, but Botox offers the longest track record; newer brands like Jeuveau can be appealing for cost or freshness.
Respuesta detallada: Botox is widely regarded as the safest “starter” neurotoxin because of decades of use, predictable effects, and broad application (cosmetic and therapeutic). Jeuveau, developed solely for aesthetics, may appeal to younger patients or those seeking a cost-effective entry point.
The best choice depends on your goals, comfort level with maintenance, and how conservative you want to be.
Q10. Is there a specific diet or supplement (like Zinc) that can extend the results of my neurotoxin?
Respuesta concisa: There is no substantial evidence that a specific diet or supplement reliably extends neurotoxin duration.
Respuesta detallada: While it’s tempting to think specific vitamins or supplements might prolong results, no robust scientific data confirms that dietary changes, including Zinc, meaningfully extend the duration of any botulinum toxin treatment.
The main factors influencing how long results last remain the toxin type, dose, injection technique, and individual metabolism.
Q11. Can I switch from Botox to Dysport, or will that mess up my results?
Respuesta concisa: Yes, you can. But dosage and injection strategy will need adjustment.
Respuesta detallada: Because units are not equivalent across brands, switching from Botox to Dysport requires recalibrating dosage (Dysport usually needs 2.5–3 times as many units for a similar effect). An experienced injector can make that switch smoothly, but it’s not a 1:1 swap.
Results should stay comparable, but the technique must change.
Q12. Is the headache I feel after my injection normal, and how long does it last?
Respuesta concisa: Yes. A mild headache can be a side effect and usually resolves within a day or two.
Respuesta detallada: Some patients report mild headaches after neurotoxin injections; this may result from the injection itself or temporary muscle relaxation in treated areas. It typically resolves within 24–48 hours.
If it persists or worsens, you should consult your provider.
Q13. Can neurotoxins be used to treat a “gummy smile,” and which one is best?
Respuesta concisa: Yes. And Botox (or a precise toxin like Xeomin or Daxxify) is often best for that.
Respuesta detallada: A “gummy smile” (excessive gingival display when smiling) can often be improved by injecting small amounts of neurotoxin into the muscles that elevate the upper labio.
Because this requires precision to avoid unwanted drift (which could affect speech or smile naturalness), using a toxin known for localized effect, like Botox, Xeomin, or Daxxify, tends to be safest.
Q14. I’m nervous about the injection spreading. Which one is the most precise?
Respuesta concisa: Xeomin and Daxxify are often considered the most precise; Botox is also reliable when appropriately performed.
Respuesta detallada: Because Xeomin is a “naked” neurotoxin without accessory proteins, and Daxxify uses a peptide stabilizer rather than proteins, both tend to diffuse less than toxins designed for broader spread. This reduces the risk of unwanted spread to adjacent muscles.
With an experienced injector, Botox can also deliver precise, controlled effects, but the formulation matters if diffusion is a concern.
Q15. Can neurotoxins help reduce pore size and facial oiliness?
Respuesta concisa: There’s limited evidence; some anecdotal reports suggest reduced oiliness or pore appearance, but this is not an FDA‑approved indication.
Respuesta detallada: Some providers and patients report that neurotoxin injections (especially with products that diffuse over larger areas, like Dysport) may lead to modest reductions in oiliness or sebaceous gland activity, which could temporarily make pores appear smaller.
However, this is not a guaranteed effect, and it is not an FDA‑approved use. Results vary widely, and more research is needed.
16. Conclusion: A Doctor’s Guide to the 6 FDA-Approved Neurotoxins: Botox Dysport Xeomin Jeaveau Letybo y Daxxify
Navigating the world of neuromodulators can feel like choosing among premium wines: though the base ingredient, botulinum toxin type A, remains the same, each “vintage” offers its own flavor, strengths, and ideal use cases.
Armed with a thorough, FDA-approved comparison of neurotoxins, patients and providers can make informed decisions tailored to individual anatomy, aesthetic goals, and lifestyle.
Whether you prioritize long‑lasting results and fewer maintenance visits (with Daxxify), pristine formulation with lower immunogenicity risk (Xeomin), broad-area smoothing (Dysport), or time‑tested precision and therapeutic versatility (Botox), there’s a neurotoxin in the toolkit that fits.
The addition of newer players, like Letybo, further expands the options, offering potential benefits influenced by global aesthetic trends.
Ultimately, the “best” neurotoxin isn’t universal.
It’s the one selected with care, administered by an experienced professional, and aligned with your personal aesthetic vision.
With that approach, you’re far more likely to enjoy natural, beautiful, and safe results.
We have covered everything about: A Doctor’s Guide to the 6 FDA-Approved Neurotoxins: Botox Dysport Xeomin Jeaveau Letybo y Daxxify.
A Doctor’s Guide to the 6 FDA-Approved Neurotoxins: Botox Dysport Xeomin Jeaveau Letybo and Daxxify
A Doctor’s Guide to the 6 FDA-Approved Neurotoxins: Botox Dysport Xeomin Jeaveau Letybo and Daxxify with Dr. Dahabra. ¿A qué esperas para liberar tu belleza?
Llámenos ahora al (954) 595-2607 o reserve online. Su viaje comienza con sólo un clic o una llamada.
Abraza la belleza, abraza la innovación - Embrace You.
17. Referencias
Treatment of Upper Facial Lines With DaxibotulinumtoxinA
JS Dover et al., 2022.
Demonstrated that DAXI (DaxibotulinumtoxinA) is efficacious and well-tolerated for simultaneous treatment of glabellar lines, forehead lines, and lateral canthal lines.
Efficacy and Safety of DaxibotulinumtoxinA for Injection in Cervical Dystonia: the ASPEN‑1 Study
CL Comella et al., 2024.
A clinical trial showed that DAXI at doses of 125 U and 250 U is effective and long‑acting in cervical dystonia, with a median duration of effect of ~20–24 weeks.
Comparison and Overview of Currently Available Neurotoxins
TJ Walker et al., 2014.
A review comparing available botulinum toxin type A products (purified vs complexed), including dose-ratio data (e.g., for IncobotulinumtoxinA (Xeomin) vs OnabotulinumtoxinA (Botox)).
Efficacy and Safety of PrabotulinumtoxinA for the Treatment of Glabellar Lines
KR Beer et al., 2019.
Two phase III, double-masked, placebo-controlled trials (EV‑001 & EV‑002) showed 20 U prabotulinumtoxinA (PrabotulinumtoxinA, brand Jeuveau) is safe and effective for moderate to severe glabellar lines.
Embracing the Versatility of Botulinum Neurotoxins in Movement Disorders
C Rasetti‑Escargueil et al., 2024.
Discusses the safety, duration of response, and efficacy of DaxibotulinumtoxinA (DAXI) in disorders such as cervical dystonia, highlighting its prolonged duration compared to older toxins.
Immunogenicity and Long-Term Use of Botulinum Neurotoxins: What We Know So Far
S Gupta et al., 2024.
A review summarizing differences between older and newer botulinum toxin A products, their formulations (complexing proteins, purified versions, newer peptide‑stabilized versions), and implications for immunogenicity, efficacy, and long-term maintenance.
Daxxify vs. Botox – How Does Daxxify Compare to Botox?
Report from the American Society of Plastic Surgeons.
A comparison summarizing onset, duration, and mechanism differences between DAXI and OnabotulinumtoxinA (Botox).
Neurotoxins Compared: Botox vs. Dysport vs. Daxxify, etc.
Arsentaul Aesthetics (2024 summary).
Offers onset-of-action comparisons (e.g., Dysport, Jeuveau, Daxxify vs Botox) and practical guidance on which toxin might suit different patient needs.
(review article discussing all main BoNT-A types, including OnabotulinumtoxinA, AbobotulinumtoxinA (Dysport), IncobotulinumtoxinA (Xeomin), PrabotulinumtoxinA (Jeuveau), and newer ones like DAXI and other emerging toxins.)
This summarizes differences in onset, duration, immunogenicity risk, and practical usage across brands.
Comparison of Botulinum Toxin Products: Dose-Ratio, Efficacy, and Safety
Sourced via PMC.
A dermatology‑oriented clinical pharmacology review that examines dose conversions (e.g., for IncobotulinumtoxinA vs OnabotulinumtoxinA), relative efficacy, and side‑effect profiles across different toxins. This underpins the concept of “unit conversion differences.”
